Local fibrinolysis

Local Intraarterial Fibrinolysis in the Carotid Territory 753

A series comprising 12 patients who had intraarterial local fibrinolysis in the carotid territory is reported. A classification is proposed that divides the different types of occlusions into three groups on the basis of angiographic location. Group 1 (two cases) comprises occlusion of the extraandfor intracranial carotid artery with patency of the circle of Willis and the lenticulostriate arte...

3412 Local intra-arterial fibrinolysis for central venous occlusion

A poor anticoagulant response to activated protein C (APC r&stance) induced hy the ArglGln8g8 mutation of the Factor V gene is, in ssversl countries, the most oommon genetic defect sssootatsd with thmmbophilic disorders. Frequencies of APC resistance between 2050% have teen observed in pstients with deep venous thrombosis, SugQedinQ the importance of the Pmtein C System acttvity. Also, in other...

Comparative Fibrinolysis

Pharmacological Fibrinolysis

Until fairly recently, arteriosclerosis and its complications were philosophically accepted as an inevitable consequence of ageing; but the steady increase of coronary deaths in particular, and the equally steady decrease ^ the age of onset have put an end to such laissez-faire complacency. To Pinpoint the epidemic acceleration of coronary deaths, a senior colleague told me that when he took th...

Local Intraarterial Fibrinolysis Administered in Aliquots for the Treatment of Central Retinal Artery Occlusion

Background and Purpose—Central retinal artery occlusion results in acute visual loss with poor spontaneous recovery. Current standard therapies do not alter the natural history of disease. Several open-label clinical studies using continuous infusion of thrombolytic agents have suggested that local intraarterial fibrinolysis (LIF) is efficacious in the treatment of central retinal artery occlus...